What is Griffonia Seed Extract? The active ingredient 5-HTP (5-Hydroxytryptophan) is a pure natural herbal formula of Griffonia Seed Extract . The ingredients are extracted from the seeds of Griffonia simplicifolia, a West African medicinal plant. It has a sedative effect. It is the predecessor of 5-HT. , Under the action of decarboxylase, 5-HT is generated, which can enhance the …