What is D chiro Inositol? D-Chiro-Inositol is a substance commonly used to treat polycystic ovary syndrome (PCOS) that may aid insulin action and help reduce insulin resistance. D-Chiro-Inositol can also help to relieve depression and can help help your liver with fat metabolism. You can find dietary inositol in many types of foods, including fruits, grains, legumes and certain meat …